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Normal vs. Pathological Aging
The line between normal and abnormal cognitive changes with age remains indistinct. Normal aging is due to physiological processes over a person’s lifetime, in which the biological clock controls development and survival of nerve cells. [ That does not exclude a spectrum of variable levels of health or a continuum within normal aging, as well as between normal and pathological aging. At one end there are individuals with “successful aging” [34]. At the other end, we find frail, easily incompensated people. According to the “threshold hypothesis” of normal aging, the reserve slowly diminishes
and a critical level may be reached. Alternatively, someone may start with a low reserve and more easily reach the threshold for the clinical manifestation of dementia as they age [35,36]. Concepts such as “benign senescent forgetfulness” [37,38], “age associated mental impairment” (AAMI) [39–41] and “mild cognitive impairment” (MCI) have been adopted to indicate alternative interpretations of cognitive decline with increasing age. The criteria for AAMI, developed by a National Institute of Mental Health work group [39], were at least 50 years of age, complaints of memory loss in everyday life, memory performance on standardized tests at least one standard deviation belo ]
Expert answered|charmine12|Points 0|
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Asked 4/2/2013 1:07:47 AM
Updated 32 days ago|1/29/2024 1:43:28 AM
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Normal aging involves expected, gradual changes in cognitive and physical functions, while pathological aging encompasses abnormal declines often associated with diseases such as dementia.

Added 32 days ago|1/29/2024 1:43:28 AM
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Not being a smoker or stopping smoking young
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Updated 32 days ago|1/29/2024 1:38:59 AM
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Not being a smoker or quitting smoking at a young age is associated with numerous health benefits, including reduced risks of various diseases such as respiratory conditions and cardiovascular issues.

Added 32 days ago|1/29/2024 1:38:54 AM
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