Question and answer
what happens when there is an insertion mutation
Insertions can be particularly hazardous if they occur in an exon, the amino acid coding region of a gene. [ A frameshift mutation, an alteration in the normal reading frame of a gene, results if the number of inserted nucleotides is not divisible by three, i.e., the number of nucleotides per codon. Frameshift mutations will alter all the amino acids encoded by the gene following the mutation.
Usually, insertions and the subsequent frameshift mutation will cause the active translation of the gene to encounter a premature stop codon, resulting in an end to translation and the production of a truncated protein. These truncated proteins frequently are unable to function properly or at all and can possibly result in any number of genetic disorders depending on the gene in which the insertion occurs. In-frame insertions occur when the reading frame is not altered as a result of the insertion; the number of inserted nucleotides is divisible by three. The reading frame remains intact after the insertion and translation will most likely run to completion if the inserted nucleotides do not code for a stop codon. However, because of the inserted nucleotides, the finished protein will contain, depending on the size of the insertion, multiple new amino acids that may affect the function of the protein ]
Get an answer
Original conversation
User: what happens when there is an insertion mutation

Weegy: Insertions can be particularly hazardous if they occur in an exon, the amino acid coding region of a gene. [ A frameshift mutation, an alteration in the normal reading frame of a gene, results if the number of inserted nucleotides is not divisible by three, i.e., the number of nucleotides per codon. Frameshift mutations will alter all the amino acids encoded by the gene following the mutation. Usually, insertions and the subsequent frameshift mutation will cause the active translation of the gene to encounter a premature stop codon, resulting in an end to translation and the production of a truncated protein. These truncated proteins frequently are unable to function properly or at all and can possibly result in any number of genetic disorders depending on the gene in which the insertion occurs. In-frame insertions occur when the reading frame is not altered as a result of the insertion; the number of inserted nucleotides is divisible by three. The reading frame remains intact after the insertion and translation will most likely run to completion if the inserted nucleotides do not code for a stop codon. However, because of the inserted nucleotides, the finished protein will contain, depending on the size of the insertion, multiple new amino acids that may affect the function of the protein ]
Expert answered|Greenpepper|Points 40|

User: what happens when there is a deletion mutation

Question
Asked 10/18/2010 8:36:24 AM
0 Answers/Comments
New answers
Rating

There are no new answers.

Comments

There are no comments.

Add an answer or comment
Log in or sign up first.
18,460,217 questions answered
Popular Conversations
Weegy Stuff
S
L
1
L
P
C
1
P
C
1
L
P
C
1
Points 2939 [Total 14649]| Ratings 11| Comments 2829| Invitations 0|Offline
S
L
Points 1479 [Total 3765]| Ratings 0| Comments 1479| Invitations 0|Offline
S
Points 872 [Total 904]| Ratings 1| Comments 862| Invitations 0|Offline
S
1
L
1
L
P
P
L
P
Points 786 [Total 14160]| Ratings 0| Comments 786| Invitations 0|Offline
S
L
Points 777 [Total 1298]| Ratings 6| Comments 717| Invitations 0|Offline
S
1
L
L
Points 273 [Total 6667]| Ratings 0| Comments 273| Invitations 0|Offline
S
L
Points 163 [Total 1459]| Ratings 3| Comments 133| Invitations 0|Offline
S
Points 128 [Total 128]| Ratings 1| Comments 118| Invitations 0|Offline
S
Points 50 [Total 50]| Ratings 0| Comments 0| Invitations 5|Offline
S
Points 46 [Total 46]| Ratings 3| Comments 6| Invitations 1|Offline
Home | Contact | Blog | About | Terms | Privacy | Social | ©2014 Purple Inc.