Will taking too much melatonin cause depression?
Sir/Madam, A few studies have shown that melatonin has worsened depression in some people. However, these studies are not without their critics, who claim the studies were flawed by small sample sizes. [ Melatonin is also known to cause an increase in prolactin, a hormone that plays a role in producing milk and in regulating the menstrual cycle. Since women experience twice the rate of
depression as men and the causes are thought to be related to hormonal cycles, women who are at risk for depression and who experience mood changes related to menstruation may wish to avoid it. ]
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